cayugad,
This is actually a very good topic. I'm going to assume you mean for inline muzzleloaders.
777 has been by far the best powder to use in an inline ML. It has been more consistent then, Goex, Pyrodex, Pinnacle, and others. Though i hate the crud ring, it's a mute point in a hunting situation.
I will say BH209 would be even better if the Muzzleloaders were built to use it. Way to many problems in most Muzzleloaders built today.