Definitely clean the barrel good before you shoot it. I have a ProHunter and it really likes 110gr of Blackhorn 209 shooting a 250gr Barnes TMZ with Harvester yellow crushed ribbed sabots and Win 209 primers. My buddy's Endeavor shoots really good with the 250gr Barnes TEZ with a Harvester black crushed ribbed sabot and a 120gr of Blackhorn 209 and CCI primers. His Endeavor's action will not close with the Win 209 so he uses the CCI's.