I just used JB on a friends .50 Encore that was a hard loader. It loads Harvester 300gr PT's in a crushed rib sabot great now. I would run about 25 passes of JB to start and clean up with Hoppes or oil of your choice. Like GM54-120 advised if the Barnes T-EZ's load tight or you do not get the accuracy you are looking for switch out the sabots for Harvester Crushed ribs as the T-EZ's are flat based.
I have good luck using CCI209M's in my .50 Omega. The .45 Omega likes Rem STS and the .45 Encore likes regular CCI primers. All use the same breechplug and like I mentioned earlier have been 100% reliable for me with Blackhorn 209.