I have a 10-ML, equipped with the Accu Trigger and a Elite 4200 scope. I use the Savage recommended Accurate powder load. Took me a while to find a suitable bullet for that powder but finally did in the Barnes 250 gr. sabot. It shoots other 250 gr. bullets well, but that one the best. Mine does not shoot 300 gr. bullets of any that I tried well at all.

The powder and bullet combo that I use will cut touching 3 to 5 shot groups more times than not. Have used it only on white tail deer. Have dropped every deer that I have shot at so far ... 11. And I killed a coyote clean at a ranged 225 yards. I lucked out on guessing the drop !!! That's for sure !!! Longest shot I have taken at deer has been about 185 yards. That buig buck dropped in its tracks, from a full pass through, shoulder crushing shot. I have tried only smokeless powder. Have no clue how it shoots with "black powder".

There are two draw backs as I see them. Both associated with the primer .... (1) Only the Winchester primer fits and (2) To set that primer in place is not simple with my old, fat fingers !!! There may eventually develop issue with the flash-hole. Looks like a pain in the butt to replace.