Those in a 300gr or with a 20-1 or #2 alloy should be a good performer. Softer lead is a bit more fussy in a sabot and more care needs to be taken when loading them. Soft lead in a sabot also tends to loosen just a tiny bit if its left loaded for long periods.
I prefer a bit of expansion but a good hard cast and a large metaplat will penetrate great on large game but still leave a hell of a wound channel.