With my scoped Remington 700ml I'm good to 150yards(never tried farther) and with my iron sighted side hammers about 80 yards max. That's my comfort zone with my ml's and I won't try no farther with them. I think ethics has alot to do with trigger control not takeing the first so so shot you get but waiting on a perfect kill shot even if it means passing up a good buck. I have made one unethical/bad shot makes me sick to this day because I rushed it and a deer suffers because of it. I was hunting a strip mine watching a huge field(500+ yards) had my 30-06 with me watching the ridges and caught something move below me in a gully I look a 6 point was standing quraryerd to me at 40 yards I threw the gun up and fired didn't account for it walking and hit it in the guts couldn't never find it lost blood trail so I learned to control my trigger finger so to speak