With all the wonderfull guns out there, there is no need to try to do it all with only one. "Honey, I really need this one to do this and that with." If I were going to choose a gun for nothing but Yotes and fox, I'd look hard at .17 Rem out to about 200 yards. (Yes, I know the .17 rem will shoot plenty farther but wind drift is a bitoch) If I was going to include other critters with it or longer distances, a .223 or .204. I would definately separate my big game stuff from my varmint stuff gun wise. Plus it more fun that way.