yes,like in my hawkins .50cal i like 80 grs of 2f for my powerbelts but would use like 70 grs or so of 3f if i wanted the same pressures.but 3f may shoot good at 80 grs.
highest i have seen in a hawkins .50 cal with 3f is around 90 grs.70/80 grs seems to be norm with 2f or 3f for best accurate shots.