I know you are looking for a number ...and I reload BUT I would have to say placement is way more important. But if I had to put a number on it 1200 lbs at impact. You left out velocity and this plays an important role. There is a point at which a lighter faster bullet will do more damage than a heavier slower bullet. so a .243 or 25-06 can do the job but its not the choice for most. That being said let the discussions begin.