Shot 3 today with the .243 and it was A LOT of FUN! I said the heck with it in purchasing rounds simply for squirrels, so I just used my deer rounds lol(100 grain softpoints) Granted as expected one of them had mass meat loss because the shot fell a little low and blew apart the sholders. However the other two were headshots and the meat was untouched. I would never hunt squirrel with my .243 but shooting them like targets for an hour or two was well worth the time. Ide do it again but im not going to plan on doing it much because like I said I like to eat squirrels. Plus nothing beats sitting at the base of trees and just plinking them off with the .22 or chasing them up the tree....too much fun in that too.