for whitetail size game,and hogs.........I would not go after elk,or moose with the 243.
Winchester 80 grain PSP has worked for me for the lsat 25 years.I have only lost one deer and that was my fault(bad hit).
I have taken in excess of 100 deer and (I would be scard to say how many hogs) in the 100' s,have never lost a hog[X(][X(];just the one deer!
thats why they make 243,270,308 , 7mm,each to his or her own.
