The bigger, the better, I always say! The ammo is expensive, but I carry my WBY .300 95% of the time. Shoots fantastically, and it is what I am most comfortable with. The other 5% of the time I carry my .270 WIN. It is a great shooting gun as well, but I just don't like it as much. Also, I have enough ammo for my Weatherby to last me at least a decade...makes it easier to go ahead and pop them off. I shoot one round before I carry it out to make sure it is still locked in, and then the only shots I take are at critters. I have had several people flame me for deer hunting with a .300 WBY MAG, but it doesn't get me down. I have more than enough confidence in the gun when I am out, and that is what matters to me. For all those who are confident in smaller calibers, I am very happy for them. I know they will kill deer just as dead. All about each individual.

That was long...sorry. My favorite caliber is .300 WBY MAG.