It depends on your ability and your gun's accuracy at varying ranges. Don't expect anything, especially with a smoothbore. Instead, go out and practice at 50, 100, 150, 200 and see how it does (i.e. GET FAMILIAR WITH YOUR GUN AND YOUR LOAD). Personally, I would never take a shot without adjustable rifle sights beyond 100 yards. MAYBE 150 if it was a perfectly broadside shot with a clear line of sight.