I've never lost a deer shooting one off of a drive...which would be.... sixteen deer I think. I have lost one while bow hunting. And no, they're not running 100 mph. But, shooting at running deer is a very hot topic hahaha. I suggets avoiding it.

But, Like I said ^^^ up there, if you do it right, the deer are just walking and sneaking to get away. If you don't push them to quick, you usually get nice shots.
-Jake