I'm only concerned with hunting, but I run vanes, straight r offset. From there, I'd not be picky. I've ran 2 and 4" and 5" vanes. So, I can't say I'd run giant ass 5" vanes cause I just can't like those for some reason I like how blazers stick to the shaft with their wide base; I like how I can get lots of 4" vanes cheap; I like that they shoot the exact same with my mechanical broadheads. I like how thick the blazers are- they can take a little abuse. I've compared normal 4" vanes and 2" blazers to 60yds side by side with no difference in accuracy (for me, but I suck and managed to keep them both inside about 6"). There's advantages to both, I hear the blazers are better for fixed blade shooters.