I know several folks that use their .220 Swift on deer with spectacular success and swear that they' re the greatest thing since sliced bread. (equivalent to .22-250.

They are owned by varmint hunters and that crowd normally are exceptionally good shooters.

I took two deer on a Texas hunt years ago with a short barreled .222 and both dropped in their tracks. I shot a springbok this summer with a .222 and it made three steps.

I use a .257 Roberts and am now upgrading it to a .260 Remington for deer, but I sure know a bunch of folks that believe that the .22-250 (and equivalent cartridges) are deer guns.