I am guessing the wet patches were causing you the headaches.

If I had that rifle... I would purchase the following

#1 pound of Pyrodex RS
three boxes of Shockwaves. Two of them in the 250 grain and one box in the 200 grain .40 caliber class (blue sabots). If your bore is real tight, get the yellow sabots on the 250 gain, or some Harvester Crushed Rib sabots in .452 diameter.

Before you even shoot... swab the bore with a slightly damp patch of your TC cleaning patches. If you need to, put them together between two boards and put that in a vice and tighten it until the fluids come out of the patches. Most the time they are too wet. OR You can ring them out with your fingers on the range. After you swab with that patch, run a dry patch down the bore. Now pop a primer. Check the dry patch and make sure it has burn marks on it. If it does, you are set to go.

On the range I would load 100 grains of Pyrodex RS and a 250 grain shockwave. I would have the target at 25 yards. I would shoot then swab, shoot then swab, and finally shoot once more. Check the group size. It should be very small. Adjust the scope to hit one and a half inches over the bull and then move the target back to 50 yards.

At 50 yards do a three shot group and check your hits. If you are satisfied, move the target back to 100 yards and try again.

Main thing is swab properly, make sure the bore is dry before you dump more powder. Sometimes it takes two dry patches to insure the bore is dry. Load consistently, and seat the ramrod with the same pressure. Also take your time between shots and concentrate. I am sure the next time out all will come together.

Good luck with your rifle. You have a great setup there.