Be aware that the higher you go......the more likely a single lung hit comes into play. It' s hard to take out both lungs shooting straight down, which you may be doing if a deer is 10 yards or closer.

The best thing about shooting at a higher angle IMO is that you can get away with more movement and if your arrow makes an exit wound it will be on the animals underside making the blood flow easily to the ground for a nice track.

Be sure of your higher shots and where they will exit.