There are better loads out there for sure. And his particular load won't make the 500 ft lb at 100yds that Colorado has. It would kill any deer at 30yds shooting it through the lungs that's a given. Hard to say if the pistol is not rated for a heavier load not sure I'd try to push that limit to find out. Maybe I'd upgrade to a ruger 45lc. I know they can handle just about anything. Buffalo bore and Core bon do make very hot loads for the 45lc. I would not be afraid to shoot a deer with Backwoods 45lc loads. Of course I never tend to aim anywhere outside the heart and lungs to try and kill anything.