The 300 XTP pushed by a powder like 296 is my heavy load for a .44 RM in a single action Ruger. I don't worry about really heavy loads in my single actions, but will not shoot them often in any double action revolver. Double action revolvers like a S&W 629 get a 240 bullet pushed by 296 as my heavy load. The 300 grain loads recoil much harder.