If weight (packing) is no issue and you want a Blackpowder gun only I say Savage 10ML.

If like me you want a gun that you can pack all day (Like CO Elk), I'd say TC Triumph, Omega, or CVA Accura.

If you want a fun gun that you can change barrels out from time to time TC Endeavor or CVA Apex.

I just bought a new .50 cal because I can't go hunt Elk in CO with a .45 cal.

Here is a picture of .45 cal TC Encore and my new .50 cal CVA Accura V2.