For 99.9 % of anything you will ever ask of a big game hunting rifle...inherent accuracy of cartridge designs will not be a factor. For a long range varminter that percentage fiqure drops considerably. For a " bench rest competitor" that difference is the difference between coming in first....or coming in last.

Contact the personnel in the ballistic' s departments at company' s like Sierra, Nosler, etc. (not customer service reps) and ask them if there is a definitive difference in ballistic efficiency and inherent accuracy from different cartridge designs. These company' s have put more time, money, and research into answering that question then the average lifetime of hunter' s will either need or want to know! (And they usually don' t even provide the custom..." made one at a time" .....bullets that the custom makers produce for many benchrest match users.)

If after your conversation with these individuals you still have any doubts?!? Let me know! But once again if you only need to know concerning " hunting accuracy" , save yourself the bother. Pick the cartridge that you believe comes closest to meeting your needs and desires...and enjoy using it!