I have taken two deer at long range with that load. 100 gr 777 and a 250 gr shockwave and 100 gr 777 and a 250 gr barnes TMZ, The first deer was 223 yards. the second was at 234 yards, Both with my Triumph. Neither went more than 20 yards. The second even had a pass through , so I know that a 250 gr bullet and a 100 gr of 777 will kill a deer over 200 yards but I wouldn't recommend shooting those distances. I have now upped my charge to 130 gr for shooting those ranges but that's because I have been using one of my Knights lately and it likes a 130 gr better.