30-06 with 150 grain winchester power points.
Why? because it's absolutely impossible to kill a deer with anything else and anyone who says otherwise is either lying or insane. And probably a spy or Al-qaeda operative. And has a crush on Nancy Pelosi.
No, the real reason is because I only own a 30-06 and the first box of ammo I bought happened to be that particular round and they grouped at an inch. Good enough for me and good enough for the deer.