If your shooting at running hogs dont blame the caliber thats just assanine.
Pulling the trigger on animal should be perfect ,if your spraying lead dont blame the caliber, thats not hunting thats shooting, or spray and pray.
I saw a less then pefect shot with my 7-08 loaned to a friend, he shot a hog in da face. knocked him down and out for good.
Ive put the same gun(caliber) through both shoulders plus 2 ribs in 2 ribs out on a big sow. Done that at least 25 times with a .243 as well. This 7-08 is my new caliber after 25 years with a .243
But I guess if spraying lead on hogs a .50 cal would be the way to go.
To me even a nasty ol hog deserves a quick clean death, no spray and pray or me, I pick my shots, if none available, Ill get him next time.