If I were wanting to use a big revolver to hunt big game up to 100 yards I would go bigger than the 44 mag. I would personally look into a Ruger Super Red Hawk in 454 Casull. A 300 grain hard cast bullet at 1600 - 1700 fps would get it done at 100 yards if you can get it there.

If you are reloading you can load mild 45 colt ammo for plinking.