I've used 25-06 with 100 gr Core Lokts and they work fine. A .243 will kill them you just have to be careful with your shot (I've killed tons with .22s on depredation permits). The condor range is a different matter and I use Barnes bullets in those areas. They are available commercially loaded for .243 by Federal and I understand Hornady has just come out with a non-lead bullet. I haven't tried those but the Barnes Triple Shock or Maximum Range work just fine. Where in Central Cal are you hunting?