I have shot 2 deer with a 150 grain bullet, both at about 50 yards. The one I shot last year went clean through, deer went maybe 20 yards and was down on the ground in 5 seconds.

The deer I shot this year (Big doe, maybe 120 lbs field dressed) was a quartering towards shot. The bullet entered in the center of the rib cage, traveled towards the hind quarters, and remarkably stopped just under the fur about 3 inches forward of the rear leg. She ran maybe 20 yards and was down in 5 seconds. I retrieved the slug and I will post a picture...very nice mushroom. That shot obviously left almost no blood trail...but then I watched her fall over so no blood trail was needed:-)