Its possible, but I would bet poor performance. Here's why. RL22 loves to run hot. Never seen a powder perform better at max pressures. In 7mm-08, it will be worse than 4350 for compression and I love that load. And you will never reach 55K CUP or 60KPSI. You will run out of room with 48gr of RL22 and it will be slow as crap.

I have never tried it. But this is just observations on experience trying slow powder in limited capacity cases like this.