I'm in MO so we can use any caliber. I was thinking that with the 15" faster burning powders could be used to get a little better powder burn, but I have not found any handgun load data for a 25-06. I have found some for the 308 however, which I am leaning heavily towards now. It's just a good all around caliber. Thanks for your input guys. One other question, a guy told me he had a 7mm bench rest barrel he'd sell me. This is a short little case, and I didn't know how well it would work on deer, or what ranges. Any info on that would be good too.