That distance with open sights is EXTREMLY difficult for anyone. If your planning on taking a long shot, you better try pushing that load as hard as you can until your accuracy begins to fail. Your'e going to get considerable drop at that range so I would suggest having your zero at 150yd minimum. Otherwise your holdover will be too high to take an ethical shot at that range. I have a hard time pulling the trigger over 100 yds or so with open sights. Although you never really clarified wether or not you would be using a scope.