Sorry you missed the doe.
It is much more than most people would guess!
Yes, it is. It has been awhile since i took a shot at a deer that was running full tilt but i've killed a lot of running hogs. Think my style is called trapping. On a hog running warp speed at right angles at 100 yards, i pick a spot in front of the animal; when animal gets about two lengths from the crosshairs i touch off the round.
My longest muzzleloader shot ever on a running animal was a sow at a lasered 227 yards last spring. Lead the sow by about 15 feet-bang flop. Yep, a lot of luck was involved.
Although this link is for a .243 bullet with a mv over 3,000 fps it will give you some idea:
http://www.udarrell.com/leading-runn...fle-frames.htm