The main thing is to know your rifle's twist in the barrel. From there you can figure what it might shoots. For instance... caliber also makes a difference, so I will address a .50 caliber for you.

1-60 or slower like a 1-101 would be a round ball shooting rifle.
1-48 is a roundball, conical, or sabot barrel. The trick is finding which one
1-32 used to be called a conical shooting barrel, but they will also shoot sabots. Even roundball is you lower the powder charge.
1-28 or faster like a 1-18 are your sabot and conical shooting barrels. Many of the modern 1-28 will shoot sabots real well.

Then you have to look at barrels with some special cut to their rifling. That too can decide what the rifle will shoot. So like I said, know your rifle.