As others have advised, the 308 Win. is a fine round for medium game hunting. I own and have hunted with many different cartridges over the past 47 years. too many to mention here. My favorite has been and clearly is the 308 Win. The 308 Win. cartridge is pretty much ideal for bullets in the 150-168 gr. range. Don't get me wrong, the 30.06 Spr. is without a doubt one of the all time great hunging cartridges. You won't go wrong with either. If you hunt bigger game that would require a hard hitting 180-200 gr. bullet for a clean kill, then of the two, go with the 30.06 Spr.