Well, most everyone here has really good points (no pun intended) about bullets. I used to get all worked up over it and finally found that when shooting at whitetail deer, any old popular brand bullet works great. After shooting many does (antelope and mule deer) I have found that the unbonded bullets (core lockt, interloc, ballistic tip's, game kings and power points) expend all of thier energy and usually drop the animal in its place or not far from it.
Now, bonded or solid bullets perform well too but they are way more expensive. Like zrex said, do you want pencil holes? Really doesnt matter if you put the bullet in the vitals.
Bigger than whitetail and mule deer? Yeah, go with a bonded or solid, you'll probably need it. EJ