I am a Wisc hunter too. But to be honest, any of the calibers you listed will work fine. I would also add the 7mm-08 which has become my favorite for hunting whitetail. But in the end, if i had only one gun it would be the 30.06. Bullet choices, power and the ability to hunt the lower 48 with it makes alot of sense. Thats not to say the others won't but the 30.06 has been around for so long because it deserves to be. Its not a fad, its a workhorse.
in today's day and age i also take ammo into consideration. What can you get when you need it now.. The calibers you mention do that. 270, 30.06 and 308 can be had at walmart if you need it. This is a big deal if you don't reload. and the best part is, it won't break the bank. $20 a box usually compared to other super calibers at over $60 a box.
i have a 30.06 and 7mm-08 for sitting in my stand. I will carry the 30.06 if standing on a drive or if driving, i will carry a 30-30 lever. Its all i ever needed.