One of the former workers at my shop is an older fellow- and he shoots an Equalizer around 50 pounds with a 27" draw and kills plenty of deer with his ACC 3-28s and (IIRC) Montec heads.
Take a look at this evaluation @ 26/50
www.archeryevolution.com/pdf/BowTechEqualizerShortDraw.pdf
That bow is getting roughly the same amount of KE at 50/26 w/ a 350 grain arrow as *I* got with one of my old bowhunting setups when I was first starting out- a Golden Eagle Predator Pro w/wheels at 72 pounds-29" draw, with overdrawn (25.5") 2213s in the 430-440 grain weight range @ 218-220 FPS. I didn't have any trouble whatsoever zipping through deer with that rig and a fixed blade head (Thunderhead 100s).
Well tuned bow- small diameter arrow with decent mass for the poundage (Axis, ACC,ST ST EPIC, etc) and a sharp small fixed blade head should be no trouble @ all with the EQ with well placed arrows.