I shot an 8 point with a 150gr Fusion from a .308 this past weekend. Bullet entered back of rib cage and exited just behind the far shoulder, slight quartering away shot. Entrance and exit wounds were both roughly the size of quarters and the buck made it about 10 yards before piling up. Was very pleased with bullet performance.
Last year I shot a yearling doe with a 95gr from my 243 and it was a 120 yard bang-flop.
Both kills have completely liquified the heart and lungs, and I've been very impressed with accuracy too. Good luck with them!