It's something not everybody does. It kinda 'weeds out' a lot of other guys, and you are more involved in the process of dealing with the components. However, I kinda think it's all very simple to change things up and experiment. Kinda handy about MLs. In handloading for centerfires, the process can get much more exact.
I also like that there's a bit more challenge to it. You have to get quite a bit closer than a centerfire to make an easy shot. Even public land isn't full of guys (round here at least). And you are probably outta luck if you miss a shot.