I'm wondering what your thoughts are on the 30-378 Weatherby Magnum, versus those of the 300 Remington Ultra Magnum.

I'm thinking that a few years down the road I want a rifle in one of these chamberings. As I handload, there is no real concern over availability of ammunition or components, nor does cost of brass need be part of the equation. In fact, let's ignore completely the components and get down to other characteristics of these two magnums.

Reloadability, design advantages or flaws, noticeable ballistic difference, ability to handle bullet sizes, etc.

Feel free to go off on a tangent about certain distinctions you feel set one apart from the other .