at 4200 fps the 22-250 can take deer at over 500 yards up to 1200 yards even. the deer drop like a rocks (bak to shot placement thing) and even if it aint a good shot the deer will die. 22-250 goes through hogs like a hot knife though butter. and those were 45g bullets...if you have a 70g i would imagine your fps will go down but it would definitely kill anything