I watched a Nosler Ballistic Tip make a crater about six inches wide and one (superficial) inch deep on the shoulder of a quartering-toward muley. Granted, it was a less than perfect shot out of a .243, but it convinced me to take the "better safe than sorry route."

I shoot 165 gr Barnes TSX out of a .30-06 for both deer and elk. Hasn't let me down yet.