Seeing as how they are all pretty similar and pretty versital cartridges, I'm going to agree with all the others and say its pretty much how they fit. I've got a 700 in a 243 win that I've had for the better part of 20 years and it still shoots great, but my favorite cartridge for deer is a .270 (got a ruger M77 in 270 win). So go and shoulder em all and see which one you wanna get. Personally, if this rifle is for deer sized game only then I would go 270. If you plan to use it for bigger definately look at the 308 or 30 -06. Anyway you go I think you're gonna be pleased.