In theory it will work but in practicality( as others have pointed out) the touch hole may not be in the proper position for fast ignition. Thompson Center Arms did produce a 54 caliber renegade with flint ignition. I have converted several rifles from percussion to flint ignition and it can be tricky.The engineering problems can be seemingly endless. My advice would be to buy or trade for a rifle that was originally built with flint ignition.
The percussion Renegade is a fine rifle in every respect that will serve you well. However, if a flintlock is really what you want you may want to look elsewhere.