What kindof worried me about your question was the: "shoot at least 100yds" part.
If you need to shoot "at least 100yds", (meaning most shots will be beyond 100yds), spitzer type bullets would probably be needed for best accuracy.
So rifle calibers are in order. As is a scope for accurate 100plus yard shots.
Id say a Super 14 contender/encore, scoped, in one of the many rifle calibers available.
I personally prefer the 10" contenders for carry, but at those kind of ranges, you'll probably have a rest, so the 14" barrel will probably help you.
Handgun hunting has become a passion of mine over the past seveal years. There is nothing like it....
Except maybe jump shooting deer in a clear cut!