Will you be hunting thick brush or open fields? I hunt thick bruch were you can only see about 30 yards in front of you so I really don't get carried away with the 150 grain powder charges. I shoot Traditions Lightning Bolts with great success with (2) 50 grain pellets and a Remington Kleenbore 209 primer with a Shockwave 250 grain. I do have a clear patch of opening into a field that I killed a doe at 110 yards with the same load. All you can do is do your time on the range and that gun will take care of you. 100 grains is plenty for whitetails even out to 200 yards but a lot depends on wind, powder amount and bullet weights. If you need to hit at 200 yards, use a light bullet weight around 200 grains loaded with 100 grains of loose or pellets and put that scope on 9 and practice at 200 yards. You should be able to dial it in for that range. If I had an area with that oportunity on a big deer and prcaticed with that load I would take the shot, pending the wind and whether or not I knew my backdrop.