I have NEVER gotten a rifle to maintain max accuracy with bullets under 300 grains. The reduced velocity attained with 300+grn bullets seems to help, I shoot the 325gr FTX in my Omega at max charge (135gr 777) and it is max accuracy (1" or a bit under) for that gun.
The same gun can only shoot the 200SW with 110gr powder, groups blow up even with 115gr.
FWIW I have a buddy who can't get over 85gr and keep groups under 1.5" with an Encore.
I have heard of people claim they get great groups with 240-250gr bullets at full charge, but never seen it with my own eyes.
I am always curious if some barrels just like a particular velocity range or something, irrespective of powder charge. The 200grSW velocity for the above load is 2050 fps while the 325grFTX load is 1950fps. All other bullets I have shot in this gun and gotten to good groups were between 1900 and 2050 fps.