Any handgun starting at .41 mag and bigger will do the trick. I' d not advise a .357 Mag for deer. You' ll like your raging bull.....Practice a lot...I never could shoot a handgun with out an optical sight. My eyes don' t focus correctly for handgun shooting so I use a red dot scope. If you find that the point of impact changes a lot from 20 yards to 100 yards, an optical assist might be in order for you too.