True story...

My buddy goes into his stand opening morning, 15 minutes after he get's settled in his tree his right leg straightens out and he realizes he's not gonna make it back to the truck!
INTESTINAL GRIDLOCK...

So he sashay's as far away as he can waddle, which is about 60 yards from his tree. Drops his camo and proceeds to paint the tree behind him (we call him wood chipper ass for a reason). He then cuts his sleeves off his shirt to wipe up, and back to his stand he goes, yet very tired from his ordeal but quite satisfied...

1 hour later a velvet 6-pointer walks into his lane and BINGO, he tags his 1st deer of the season.

Every season on "archery eve" I leave him a voice mail that goes something like Tammy Wynette's song, but I like to call the title "Chit Bye Your Stand", come on everyone sing along...

So to answer your question...
If you know your deer patterns you could use your discomfort as part of your strategy!