Most of my experience has been with the 7mm Remington Magnum. Due to hunting location (both geography and terrain), I prefer a shot through the front shoulder and both shoulders if possible (I have never had a deer do anything but drop from that shot).
All entry wounds have been caliber sized. The exit wounds have varied in size from a respectable 5 inch diameter hole with Winchester Ballistic Silvertips, to a basketball size hole with 140 grain Core-lokts, to one deer nearly blown in two (only skin on the back and belly holding it together...deer fell in two pieces upon skinning) from a 160 grain Nosler Partition.
The 7mm RM is obviously overgunning for deer, but at least there is no arguement with the next guy around the hill because my deer do not run that far.
BTW--the distances for those wounds were 80 yards, 265 yards, and 65 yards respectively. I am currently using the Winchester BSTs.